Data Manager leading clinical-trial database, validation, reconciliation, and lock activities for ClinChoice, a global full-service CRO. Hybrid permanent role in Mississauga, Ontario.
Responsibilities
Lead data management activities for clinical trials, including database setup, study conduct, and close-out
Ensure study deliverables meet timelines and quality standards
Review clinical research documents, including protocols and Case Report Forms
Create and review electronic Case Report Form specifications
Develop Data Management Plans, Data Validation Plans, eCRF Completion Guidelines, Data Entry Guidelines, and Data Review Plans
Develop edit rules, checks, query logic, and query messages
Develop User Acceptance Testing Plans and test data-entry screens and edit checks
Create and provide training to clinical teams and sites
Perform ongoing data review and reconciliation activities
Provide metrics and patient trackers to monitor data cleanup
Perform database lock/unlock and freeze/unfreeze activities for statistical review, interim analysis, and final database lock
Coordinate archiving of study databases and related documents
Create Data Transfer Specifications and perform external vendor reconciliation
Perform SAE reconciliation
Maintain and improve client satisfaction through high-quality service, communication, and clinical data management
Requirements
Bachelor’s degree in clinical/pharmacy biological/mathematical sciences or related field or nursing degree
At least 3 years of data management and/or related work experience in the pharmaceutical industry
Working knowledge of clinical research, clinical trial processes, regulatory requirements, and terminology
Strong knowledge and experience with several electronic data capture systems, such as Medidata Rave, Oracle InForm, OpenClinica, and Medrio
Perform duties in compliance with SOPs, GCP, and ICH guidelines
Ability to prioritize and adapt quickly in fast-paced and changing industry conditions
Ability to lead a study or data management team independently
Ability to drive quality and efficiency to meet timelines and milestones
Excellent verbal and written communication skills
Proficient in Microsoft Office, including Outlook, Word, Excel, and PowerPoint
Benefits
Permanent employment
Hybrid work arrangement
Equal opportunity employer
Inclusive, barrier-free recruitment and selection processes
Accommodation for qualified applicants under the Human Rights Code and the Accessibility for Ontarians Disabilities Act
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